Rudnicki C., Forys S., Stec-Michalska K. et al. Usefulness of electrogastrography in the differencial diagnosis of clinical forms of functional dyspepsia // Gut 2009; 58 (Suppl II) A132.

Авторы: Rudnicki C. / Forys S. / Stec-Michalska K. / Chojnacki J. / Wisniewska-Jarosinska M.A.

GASTRO 2009 UEGW/WCOG
21-25 November 2009, London – United Kingdom
Oesophageal, gastric and duodenal disorders I

Usefulness of electrogastrography in the differencial diagnosis of clinical forms of functional dyspepsia

C. Rudnicki, S. Forys, K. Stec-Michalska, J. Chojnacki, M.A. Wisniewska-Jarosinska
  Department of Gastroenterology nad Internal Diseases, Medical University of Lodz, Lodz, Poland

INTRODUCTION: The pathogenesis of functional dyspepsia is still not clear, but the disorders of the motility and myoelectrical activity of the stomach play here a very important role.

AIMS & METHODS: The aim of this study was to evaluate gastric myoelectrical activity in patients suffering from functional dyspepsia (FD) and to answer the question if there are some differencies between two clinical forms of FD. A group of 60 patients diagnosed with FD, aged 18-65 years (mean age 34.8 + 12.1), and a refrence group of 30 healthy volunteers aged 18-65 (mean age 38.2 + 18.4) were tested. FD was diagnosed according to the Rome III Criteria. 30 persons tested presented symptoms of postprandial distress syndrome (PDS), whereas the other half (n = 30) epigastric pain syndrome (EPS). Helicobacter pylori infection was excluded by UBT-13C. Cutaneous electrogastrography (EGG) was recorded using Polygraf ID 8-channel (Medtronic). After an hour recording of the gastric myoelectrcal activity in patients at fasting conditions, a solid or liquid test meal was served (400 kcal) and the recording was repeated.

RESULTS: In the patients with FD gastric myoelectrical disorders occurred with a dominance of dysrhythmia (p < 0.001), especially bradygastria recorded both at fasting and after a meal. The EGG records showed differences in the two forms of FD. In the group with PDS there was statistically significant more tachygastria both in the total recording period (t = 2.719; p < 0.01) and after a meal (t = 2.164; p < 0.05) than in the group of patients with EPS.

CONCLUSION: In the patients with FD gastric myocardial disorders occur with dominating dysrhythmia, especially bradygastria. The EGG records are different in the two clinical forms of FD and this may be used for the differential diagnosis of the various forms of this disease.

Reference:

1. Leahy A, Besherdas K, Clayman C et al.: Abnormalities of the electrogastrogram in functional gastrointestinal disorders. Am J Gastroenterol 1999; 94: 1023-1028.

2. Lin Z, Chen JD, Parolisi S et al.: Prevalence of gastric myoelectrical abnormalities in patients with nonulcer dyspepsia and H. pylori infection: resolution after H. pylori eradication. Dig Dis Sci 2001; 46(4): 739-45.

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